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Sam's News — diet-exercise — 2026-09-03

Health

7.5 Immune receptor blocking may reverse aging in mice

Stanford Medicine researchers found that blocking a single immune receptor on tissue-resident macrophages restored their ability to clear senescent neutrophils, reducing inflammation and maintaining youthful function across multiple organs in aged mice. The intervention protected mice from frailty, excess fat accumulation, heart trouble, and substantially reduced cognitive decline. The findings suggest aging may be partly driven by immune cells losing their ability to dispose of damaged, inflammation-promoting cells.

  • Blocking single immune receptor restored cellular cleanup in tissue macrophages
  • Effects observed across brain, heart, skeletal muscle, liver, spleen, kidney, and colon
  • Protected mice from frailty, excess fat, and heart trouble
  • Substantially reduced cognitive decline in aged mice
  • Published in Science with Katrin Andreasson as senior author

Sources: ScienceDaily AI Web Searched, ScienceDaily — Health RSS, ScienceDaily — Fitness RSS